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Targeted immunotherapy in Hodgkin lymphoma

Hutchings M.
Blood. 2015 Jun 25; 125(26): 3967-8.doi: 10.1182/ blood-2015-05-641712./.

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EGFRvIII TandAbs are specific and highly potent drug candidates for the treatment of a variety of solid tumors

Ellwanger et al.
CIMT 2015

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A tetravalent bispecific TandAb (CD19/CD3), AFM11, efficiently recruits T cells for the potent lysis of CD19(+) tumor cells

Reusch et al.
MAbs. 2015 May 4;7(3):584-604. doi: 10.1080/19420862.2015.1029216. [PubMed - in process].

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In vitro and in vivo killing of AML using tetravalent bispecific CD33/CD3 TandAbs

Eissenberg et al.
ASCO 2015

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Development Of A Bispecific Tetravalent CD33/CD3 TandAb For The Treatment of AML

Reusch et al.
ASCO 2015

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Construction and Characterization of Novel CD33/CD3 Tandem Diabodies (TandAbs®) for the Treatment of Acute Myeloid Leukemia (AML)

Reusch et al.
ASCO 2015

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TandAbs: potent and well-manufacturable bi-specific antibodies

Weichel et al.
European Pharmaceutical Review 2015 20(1): 27-32

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Specific NK cell activation to treat relapsed/refractory (r/r) Hodgkin Lymphoma (HL) patients – final, updated data on clinical outcome, pharmacokinetics and pharmacodynamics of a phase 1 study investigating AFM13, a bispecific anti- CD30/CD16A TandAb

Rothe et al.
ASH 2014

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A CD19/CD3 bispecific TandAb, AFM11, recruits T cells to potently and safely kill CD19+ tumor cells in pre-clinical models

Reusch et al.
PEGS 2014

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A novel tetravalent bispecific TandAb (CD30/CD16A) efficiently recruits NK cells for the lysis of CD30+ tumor cells.

Reusch et al.
MAbs. 2014 Mar 26;6(3).

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