Affimed (Nasdaq: AFMD) is a clinical stage biopharmaceutical company which engineers targeted immunotherapies, seeking to improve patient outcomes through the power of innate immunity. Affimed’s fit-for-purpose ROCK® platform allows innate immune engagers to be designed for specific patient populations. We are developing single and combination therapies to treat cancers.

To strengthen our Translation & Innovation Department in Heidelberg, Germany, we are looking for a

Head of Innate Cell Therapies

(Reference No. R2112)

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Responsibilities

  • Act as a subject matter expert in the field of cell-based cancer immunotherapies within a scientific strategy and development team
  • Build scientific rationale and drive experimental work to establish combination therapies of Affimed’s innate cell engagers and adoptive cellular therapy
  • Build and lead a research team engaged in the experimental design and execution of functional studies to support the development of Affimed’s drug candidates
  • Present project status updates as well as new and innovative project ideas on a regular basis in meetings with different audiences, e. g. preclinical teams, cross-functional program teams, and the management team
  • Initiate and lead external research collaborations and ensure deliverables are on time, on budget, and of high quality
  • Integrate latest findings from key-relevant publications, supporting further development of ongoing as well as novel projects

Requirements

  • Advanced degree (M.D. or Ph.D. in life sciences) with relevant experience in cellular cancer immunotherapies
  • At minimum, five years of clinical/translational research experience in a clinical, biotechnology, or pharmaceutical industry setting, preferably with a strong focus on the development of cellular therapies
  • Specific knowledge on innate immune cells including their genetic modification is a plus
  • Experience with closed systems and cell processing equipment such as CliniMACS, CliniMACS Prodigy, Sepax, Xuri, G-Rex, and controlled rate freezer
  • Experience in large-scale preparation of cell fractions from leukapheresis products, subsequent in vitro expansion, and functional characterization
  • In-depth knowledge of immunology and tumor biology, including relevant markers, immune cell populations, and cellular crosstalk within the tumor microenvironment
  • Experience in leading a research laboratory
  • Ability to independently design and execute experiments, including the interpretation of experimental data
  • Good understanding of regulatory and quality requirements for GMP-compliant production of cell products
  • Strong capabilities in relationship building with team members and external partners, ensuring successful collaboration
  • Experience in driving projects according to timelines, budget and quality
  • Excellent communication skills covering a broad range of audiences, including research teams, cross-functional program teams and the management team
  • Fluent in English (oral & written), German language skills is a plus

Opportunity

The successful candidate will have the unique opportunity to work in a dynamic, highly motivated, multidisciplinary and collegial team.
For any queries, please contact Susanne Hering (Tel: 06221 6743 675, e-mail: s.hering@affimed.com).
Please send your application by using the following link: http://www.affimed.com/careers.php

October 2021

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