Affimed (Nasdaq: AFMD) is a clinical stage biopharmaceutical company which engineers targeted immunotherapies, seeking to improve patient outcomes through the power of innate immunity. Affimed’s fit-for-purpose ROCK® platform allows innate immune engagers to be designed for specific patient populations. We are developing single and combination therapies to treat cancers.

To strengthen our growing team in Heidelberg, Germany, we are looking for a

Scientist (MD/PhD) – Tumor Biology (f/m/d)

(Reference No. OP2006)

This position is initially limited to one year with an option of extension and the opportunity to transform into Translational Project Leader Immuno-Oncology


  • Act as a subject matter expert in a key-relevant area of immuno-oncology as member of a scientific strategy and development team, supporting the development of novel cancer immunotherapeutics
  • Experimental design of in vitro studies to support the development of Affimed’s drug candidates and its ROCK® platform
  • Present project status updates as well as new and innovative project ideas on a regular basis in meetings with different audiences, e.g. preclinical teams and cross-functional program teams and management team
  • Establish the scientific rationale and experimental design of translational research to support clinical development of Affimed’s drug candidates and to implement key findings from clinical studies to drive innovative adaptation of drug candidates
  • Initiate and drive all aspects of translational research in development programs in close collaboration with the cross-functional program teams
  • Initiate and lead external translational research collaborations and ensure its deliverables in time, budget and high quality
  • Integrate latest findings from key-relevant publications, supporting further development of ongoing as well as novel projects


  • Education as MD/Ph.D. or PhD or MD with relevant experience in immuno-oncology
  • 5 years of experience in clinical/translational research in a clinical, biotech or pharmaceutical industry environment
  • In depth knowledge of immunology and tumor biology, including relevant markers, immune cell populations and cellular crosstalk within the tumor microenvironment
  • Leadership skills and experience in independently leading a research laboratory
  • Ability to independently design and execute experiments, including the interpretation of experimental data
  • Hands-on experience and knowledge of state-of-the-art cell-based in vitro assays and techniques such as isolation and culture of primary immune cells, fluorescence activated cell sorting, ELISA, trans-well-, proliferation-, and cytokine release assays
  • Experience in preclinical development of antibody and / or cell-based therapeutics is of advantage
  • A solid understanding of drug discovery, clinical development, biochemistry, molecular biology, cancer biology
  • Strong capabilities in relationship building with team members and external partners, ensuring successful collaboration
  • Experience in driving projects according to timelines, budget and quality
  • Excellent communication skills covering a broad range of audiences, including research teams, cross-functional program teams and management
  • Fluent in English (oral & written), German language skills desirable


The successful candidate will have the unique opportunity to work in a dynamic, highly motivated, multidisciplinary and collegial team.

For any queries, please contact Susanne Hering (Tel: 06221 6743 675, e-mail:

May 2020

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