Scientific Publications

Below is a selection of scientific publications providing a comprehensive insight in the field of monoclonal antibodies generated through our projects by our team, our collaborators and renowned scientific experts in antibody research. If you require electronic copies of the publications listed below or further information please contact Claudia Heisch.

Claudia Heisch - General Contact - Affimed

c.heisch@affimed.com

Phonework: + 49 6221 65307 35

Fax: + 49 6221 65307 77

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  • (68)Ga-labelled recombinant antibody variants for immuno-PET imaging of solid tumours.

    Authors: Eder M, Knackmuss S, Le Gall F, Reusch U, Rybin V, Little M, Haberkorn U, Mier W, Eisenhut M.

    Publication details: 2010. Eur J Nucl Med Mol Imaging.

  • Alternative antibody formats. In “Recombinant Antibodies for Immunotherapy”.

    Authors: Le Gall F and Little M.

    Editor: Melvyn Little.

    Publication details: publ. Cambridge University Press, 2009.

  • Recombinant Antibodies for Immunotherapy.

    Authors: various

    Editor: Little M

    Publication details: Publ. Cambridge University Press, 2009.

  • Tetrafluorophenolate of HBED-CC: a versatile conjugation agent for 68Ga-labeled small recombinant antibodies.

    Authors: Eder M, Waengler B, Knackmuss S, LeGall F, Little M, Haberkorn U, Mier W, Eisenhut M.

    Publication details: 2008. Eur J Nucl Med Mol Imaging, 35 (10): 1878 - 86.

  • Effect of tetravalent bispecific CD19xCD3 Recombinant Antibody construct and CD28 costimulation on lysis of malignant B Cells from patients with chronic Lymphocytic leukemia by autologous T Cells.

    Authors: Reusch U, Le Gall F, Hensel M, Moldenhauer G, HO AD, Little M and Kipryanov S.

    Publication details: 2004. Int. J. Cancer: 112: 509–518.

  • Immunosuppressive properties of anti-CD3 single-chain Fv and diabody.

    Authors: Le Gall F, Reusch U, Moldenhauer G, Little M and Kipriyanov S.

    Publication details: 2004. Journal of Immunological Methods, 285: 111 –127.

  • Effect of linker sequences between the antibody variable domains on the formation, stability and biological activity of a bispecific tandem diabody.

    Authors: Le Gall, Reusch U, Little M and Kipriyanov S.

    Publication details: 2004. Protein Engineering, Design & Selection vol. 17 no. 4: 357–366.

  • Generation and Production of Engineered Antibodies.

    Authors: Kipriyanov S and Le Gall F.

    Publication details: 2004. Moleculear Biotechnology, 26: 39 – 60.

  • Effect of Domain Order on the Activity of Bacterially Produced Bispecific Single-chain Fv Antibodies.

    Authors: Kipriyanov S, Moldenhauer G, Braunagel M, Reusch U, Cochlovius B, Le Gall F, Kouprianova O, Von der Lieth CW and Little Melvyn.

    Publication details: 2003. J Mol Biol 330: 99 - 111.

  • Generation of Bispecific and Tandem Diabodies.

    Authors: Kipriyanov S.

    Editor: P.M. O’Brien, R. Aitken

    Publication details: Methods in Molecular Biology, vol. 178: Antibody Phage Display: Methods and Protocols. © Humana Press Inc., Totowa, NJ.

  • Synergistic Antitumor Effect of Bispecific CD19 x CD3 and CD19 x CD16 Diabodies in a Preclinical Model of Non-Hodgkin’s Lymphoma.

    Authors: Kipriyanov S, Cochlovius B, Schaefer H, Moldenhauer G.

    Publication details: 2002. Journal of Immunology, 169: 137 – 144.

  • Recombinant chimeric OKT3/IgM antibodies for immune suppression: evaluation in a human CD3 transgenic mouse model.

    Authors: Choi I, Schmitt WE, Baehre A, Little M and Cochlovius B.

    Publication details: 2002. Immunology Letters, 80: 125 – 128.

  • Recombinant chimeric OKT3 scFv IgM antibodies mediate immune suppression while reducing T cell activation in vitro.

    Authors: Choi I, De Ines C, Kürschner T, Cochlovius B, Sörensen V, Olafsen T, Sandlie I and Little Melvyn.

    Publication details: 2001. Eur. J. Immunol, 31: 94–106.

  • Of mice and men: hybridoma and recombinant antibodies.

    Authors: Little M, Kipriyanov S, Le Gall F and Moldenhauer G.

    Publication details: 2000. Immunology Today, 21 (Nr 8): 364 - 370.

  • Treatment of Human B Cell Lymphoma Xenografts with a CD3 x CD19 Diabody and T Cells.

    Authors: Cochlovius B, Kipriyanov S, Stassar M, Christ O, Schuhmacher J, Strauß G, Moldenhauer G and Little M.

    Publication details: 2000. Journal of Immunology, 165: 888–895.

  • Cure of Burkitt’s Lymphoma in Severe Combined Immunodeficiency Mice by T-Cells, Tetravalent CD3 x CD19 Tandem Diabody, and CD28 Costimulation.

    Authors: Cochlovius B, Kipriyanov S, Stassar M, Schuhmacher J, Benner A, Moldenhauer G and Little M.

    Publication details: 2000. Cancer Research 60: 4336 - 4341.

  • Generation of Recombinant Antibodies.

    Authors: Kipriyanov S and Little M.

    Publication details: 1999. Molecular Biotechnology. Vol 12: 173.

  • Bispecific Tandem Diabody for Tumor Therapy with Improved Antigen Binding and Pharmacokinetics.

    Authors: Kipriyanov S, Moldenhauer G, Schuhmacher J, Cochlovius B, Von der Lieth CW, Matys ER and Melvyn Little.

    Publication details: 1999. J. Mol. Biol. 293: 41-56.